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Thanasekaran Jayakumar Selected Research

rutecarpine

5/2022Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules.
1/2022Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB.
10/2021Rutaecarpine, an Alkaloid from Evodia rutaecarpa, Can Prevent Platelet Activation in Humans and Reduce Microvascular Thrombosis in Mice: Crucial Role of the PI3K/Akt/GSK3β  Signal Axis through a Cyclic Nucleotides/VASP-Independent Mechanism.

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Thanasekaran Jayakumar Research Topics

Disease

13Neoplasms (Cancer)
05/2020 - 01/2013
10Thrombosis (Thrombus)
01/2022 - 06/2016
10Inflammation (Inflammations)
12/2021 - 01/2014
7Pulmonary Embolism
01/2022 - 12/2011
7Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
04/2020 - 01/2011
6Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 08/2012
6Stroke (Strokes)
04/2019 - 01/2013
5Brain Ischemia (Cerebral Ischemia)
07/2017 - 01/2011
4Ischemic Stroke
04/2020 - 04/2016
3Embolic Stroke
04/2020 - 09/2014
3Infarction (Infarctions)
01/2017 - 01/2013
3Melanoma (Melanoma, Malignant)
09/2015 - 01/2014
3Hypoxia (Hypoxemia)
09/2014 - 01/2011
3Reperfusion Injury
01/2014 - 01/2013
2Obesity
05/2022 - 06/2019
2Brain Injuries (Brain Injury)
07/2017 - 04/2016
2Ulcer
01/2017 - 01/2014
2Brain Infarction
01/2017 - 04/2016
2Wounds and Injuries (Trauma)
01/2017 - 01/2014
2Ischemia
01/2017 - 01/2014
2Thromboembolism
02/2016 - 12/2010
2Chondrosarcoma
04/2013 - 05/2011
1Joint Diseases (Joint Disease)
07/2020
1Necrosis
07/2019
1Renal Insufficiency (Renal Failure)
06/2019
1Schizophrenia (Dementia Praecox)
01/2019
1Atherosclerosis
11/2018
1Vascular Diseases (Vascular Disease)
04/2018
1Lung Neoplasms (Lung Cancer)
03/2018
1Adenocarcinoma
03/2018
1Adenocarcinoma of Lung
03/2018
1Cerebral Infarction
01/2017
1Brain Edema (Cerebral Edema)
01/2017
1Acute Coronary Syndrome
06/2016

Drug/Important Bio-Agent (IBA)

6Adenosine Diphosphate (ADP)IBA
01/2022 - 12/2011
6Matrix Metalloproteinases (MMPs)IBA
07/2020 - 05/2011
6beta-thujaplicinIBA
04/2018 - 01/2013
6andrographolideIBA
07/2017 - 12/2011
5Neuroprotective AgentsIBA
07/2017 - 01/2013
4Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
07/2019 - 01/2011
4Caspase 3 (Caspase-3)IBA
01/2015 - 01/2011
3rutecarpineIBA
05/2022 - 10/2021
3platonin (NK 19)IBA
04/2020 - 01/2014
3EnzymesIBA
03/2018 - 05/2014
3AntioxidantsIBA
03/2018 - 05/2014
3TropoloneIBA
05/2015 - 01/2013
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2014 - 01/2011
3Glucose (Dextrose)FDA LinkGeneric
05/2014 - 01/2014
2Biological ProductsIBA
05/2022 - 12/2021
2AlkaloidsIBA
05/2022 - 10/2021
2Pharmaceutical PreparationsIBA
01/2022 - 01/2017
2IntegrinsIBA
05/2020 - 11/2019
2RutheniumIBA
04/2020 - 07/2019
2PlatinumIBA
05/2018 - 12/2017
2Hydroxyl RadicalIBA
01/2017 - 01/2015
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2017 - 06/2016
2Troleandomycin (TAO)FDA Link
01/2017 - 01/2011
2Mitogen-Activated Protein KinasesIBA
04/2016 - 01/2014
2p38 Mitogen-Activated Protein KinasesIBA
04/2016 - 01/2014
2Proteins (Proteins, Gene)FDA Link
09/2015 - 11/2012
2Tissue Plasminogen Activator (Alteplase)FDA Link
02/2015 - 09/2014
2sesamolIBA
05/2011 - 12/2010
13- (4- methylphenylsulfonyl)- 2- propenenitrileIBA
01/2022
1PhytochemicalsIBA
12/2021
1SphingolipidsIBA
12/2021
1Cyclic NucleotidesIBA
10/2021
1resorcinol (resorcin)IBA
04/2021
1Reticulin (Reticular Fiber)IBA
04/2021
1Rosaniline Dyes (Fuchsin)IBA
04/2021
1CarbonIBA
06/2020
1Analgesics (Analgesic Drugs)IBA
05/2020
1columbianadinIBA
05/2020
1CymenesIBA
04/2020
1quinolineIBA
04/2020
1auraptenIBA
11/2019
1Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2019
1esculetinIBA
06/2019
1CoumarinsIBA
06/2019
1coumarinIBA
06/2019
1TubulinIBA
04/2019
1Poly I-CIBA
01/2019
1Hemostatics (Antihemorrhagics)IBA
11/2018
1FlavonoidsIBA
08/2018
1morinIBA
08/2018
1MetalsIBA
05/2018
1Cisplatin (Platino)FDA LinkGeneric
05/2018
1Monoterpenes (Monoterpenoids)IBA
03/2018
1pyridineIBA
12/2017
1Organometallic CompoundsIBA
12/2017
1IridiumIBA
12/2017
1DiterpenesIBA
07/2017
1LactonesIBA
07/2017
1Therapeutic UsesIBA
07/2017
1triphenyltetrazoliumIBA
01/2017
1Coloring Agents (Dyes)IBA
01/2017
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
06/2016
1zinc protoporphyrinIBA
04/2016

Therapy/Procedure

2Therapeutics
04/2019 - 02/2015
2Renal Dialysis (Hemodialysis)
08/2013 - 11/2012
1Chemoprevention
03/2018